Kinase Inhibitor Cardiotoxicity Database (KICDB): A Causality-Oriented Multi-Omics Database for Kinase Inhibitor-Induced Cardiotoxicity

We developed the Kinase Inhibitor Cardiotoxicity Database (KICDB), a comprehensive and interactive web server built upon a framework integrating large-scale transcriptomics meta-analysis with causal inference. This database centralizes findings from 26 kinase inhibitors across 7 studies (n=5291) to explore underlying causal mechanisms of inhibitor-induced cardiotoxicity.